With a City euthanized at 3

LEXINGTON, Ky. - With a City, the 48-1 winner of the $500,000 Lane's End Stakes on March 25 and an intended starter in the Kentucky Derby, was euthanized on Sunday at a Lexington-area horse clinic after displaying symptoms that included diarrhea and seizures for several days, according to his trainer, Mike Maker.

The cause of death has not been determined, Maker said on Monday. Veterinarians who treated With a City have ruled out several infectious diseases, including equine herpesvirus, Maker said, and the horse's "small and large intestines scanned clean," indicating that the initial prognosis did not include common reasons for a sudden debilitating condition such as toxic shock or colitis.

"They tested and treated him for everything," Maker said. "His vital signs were fine, and he never spiked a temperature." A necropsy has been ordered, Maker said, and results will likely be available later this week.

was owned by Ron Peltz, the manager of the racing syndicate Equirace.com and a horse owner for 18 years. Maker said that Peltz had an insurance policy covering mortality, and that Peltz was the only owner. Peltz bought With a City for a reported $150,000 after a win Dec. 29 at Calder Race Course in a first-level turf allowance race. Three months later, With a City won the Lane's End. In his final race, With a City finished last of 13 in the Arkansas Derby at Oaklawn Park on April 15.

According to Maker, With a City was admitted to Hagyard Equine Medical Institute outside Lexington on Wednesday evening after suffering from severe diarrhea. Over the next several days at the clinic, With a City began suffering seizures, Maker said. At the time, With a City was being administered sedatives to calm him down.

"When we took him in, he was bright and happy and alert, but he went downhill fast from there," Maker said. "He started having seizures, and the vets would find him lying down on the ground, thrashing like he was trying to run."

An official at Hagyard said on Monday that the clinic's policy prevents anyone at the hospital from speaking about a specific case.

Maker said that With a City had not been administered any drugs before suffering the bout of diarrhea. No other horses in Maker's barn have displayed any symptoms that were similar to those that afflicted With a City, Maker said.

Peltz did not return a phone call Monday. A notice was posted on Equirace.com that said that "for reasons only God can explain, With a City took ill on Wednesday afternoon. And died on Sunday."

With a City's career record was 4 wins and 2 seconds from 12 starts, with the vast majority of his total earnings, $359,980, coming from the $300,000 winner's share of the Lane's End purse. With a City was trained at the Trackside training center in Louisville, where Maker, a longtime assistant to D. Wayne Lukas who went out on his own three years ago, is based.