A lot can go wrong in three months – especially in racing. Mike Puype considers himself very fortunate that not only has Turbulent Descent flourished in her training toward the $1 million Breeders’ Cup Filly and Mare Sprint since she won her last start, the Aug. 6 Test at Saratoga, but also that the competition for his star 3-year-old filly in this upcoming seven-furlong race could have been considerably stronger than what appears to be materializing.

ARCADIA, Calif. -- Zazu, the winner of three graded stakes this year, will not start in the Breeders' Cup Ladies' Classic at Churchill Downs on Nov. 4 after inflammation was detected in a shoulder, trainer John Sadler said on Wednesday.

"We're going to bypass the Ladies' Classic," Sadler said. "She came out of her work a little off. We put her in the nuclear scan, and it revealed a little inflammation. The timing is lousy, but the prognosis for next year is 100 percent."

Jockey Ramon Dominguez is a man in demand for the Breeders’ Cup Ladies’ Classic Nov. 4 at Churchill Downs. He is the regular rider of Havre de Grace, and though she is far more likely to run against males in the Classic on Nov. 5, his assignment for this race is not nailed down. And it’s getting more complicated.

Though he remains focused primarily on the Breeders’ Cup Classic, trainer Todd Pletcher said Wednesday that he would likely pre-enter Uncle Mo in the $1 million Dirt Mile as well.

“We will probably pre-enter in the Mile as a second choice,” said Pletcher, who trains Uncle Mo for Mike Repole. “I suppose just as an insurance policy. There’s no harm in pre-entering him.”

Uncle Mo came out of his five-furlong breeze in 58.42 seconds on Sunday in good order, according to Pletcher.

Seventeen racetracks have agreed to participate in a mystery mutuel voucher promotion offered by Breeders’ Cup that could award someone a $500,000 payout, according to the organization.

The racetracks are Aqueduct, Belmont, Canterbury Park, Charles Town Races, Emerald Downs, Gulfstream Park, Hollywood Park, Keeneland, Laurel, the Meadowlands, Monmouth, Penn National, Pimlico, Santa Anita, Saratoga Raceway harness track, Suffolk Downs, and Sunland Park, Breeders’ Cup said.

The unbeaten Juvenile Fillies favorites My Miss Aurelia and Grace Hall are established, professional Grade 1 winners who are training well.

Others are longshots, with work to do.

Miss Netta has starting-gate issues that became evident when she missed the break and finished nine lengths behind My Miss Aurelia in the Grade 1 Frizette.

Rocket Twentyone will try to win the first two-turn race of her career while starting for the first time in 55 days.

Aside from those owners whose horses won Win and You’re In races, resulting in expense-paid berths to the Breeders’ Cup, participating owners in the Breeders’ Cup must ante up a sizable 3 percent of the race purse to pre-enter and start their horse.

Less than a week before pre-entries are made for the Breeders’ Cup, trainer Pat Byrne is playing the waiting game, wondering if his promising 2-year-old Take Charge Indy can gain entry into the Breeders’ Cup Juvenile.

Although uncertain of making the race if it is oversubscribed as is typically the case from year to year, the chances of his horse making the field appear better this week than last.

Trainer Peter Walder got a pretty good feel for what it’s like winning a Breeders’ Cup race last year when he joined his girlfriend, trainer Diane Alvarado, both in the winner’s circle and on the podium for the post-race press conference following Eldaafer’s victory in the Marathon. On Nov. 5, Walder will attempt to experience an even bigger thrill, saddling a Breeders’ Cup winner of his own, when he sends out Force Freeze in the Breeders’ Cup Sprint.

Regally Ready, whose four-race win streak earlier this year was capped by a score over Bridgetown and Chamberlain Bridge in the Grade 3 Twin Spires Turf Sprint at Churchill Downs on Kentucky Derby Day, got back on track with a front-running upset of last Sunday’s Grade 1, $511,600 Nearctic Stakes at Woodbine. The Steve Asmussen-trained gelding earned a fees-paid berth to the Grade 2 Breeders’ Cup Turf Sprint after prevailing over 2-1 favorite Bated Breath by a neck on a yielding course.