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NFL Schedule Release: Ranking the Top 5 Games in 2022

By Nick Fata
Quarterback Josh Allen will lead the Bills against the Rams on Sept. 8.
© Jamie Germano / USA TODAY NETWORK
  • 09/08 8:20 PM ET
    Spread
    ML
    Score
    451BUFBUF
    -2
    -130
    31
    452LARLAR
    52
    110
    10
  • 09/11 1:00 PM ET
    Spread
    ML
    Score
    453BALBAL
    -6.5
    -260
    24
    454NYJNYJ
    44
    220
    9
  • 09/11 1:00 PM ET
    Spread
    ML
    Score
    455NONO
    -5.5
    -220
    27
    456ATLATL
    44
    180
    26
  • 09/11 1:00 PM ET
    Spread
    ML
    Score
    459CLECLE
    42
    105
    26
    460CARCAR
    -1.5
    -125
    24
  • 09/11 4:25 PM ET
    Spread
    ML
    Score
    471KCKC
    -6.5
    -260
    44
    472ARZARZ
    54
    220
    21
  • 09/11 8:20 PM ET
    Spread
    ML
    Score
    479TBTB
    -2.5
    -140
    19
    480DALDAL
    49.5
    120
    3
  • 09/12 8:15 PM ET
    Spread
    ML
    Score
    481DENDEN
    -6
    -230
    16
    482SEASEA
    43.5
    190
    17

The 2022 NFL schedule has finally been released, and to say there are a few matchups to look out for would be an understatement. But, if we have to pick, here are a few key exciting matchups to look out for this season.

Week 1: Bills @ Rams

The Buffalo Bills are arguably the best team in football… maybe behind the defending Super Bowl Champion Los Angeles Rams. Not only will this game be fun to watch, but also an early prove it game for both teams. Can the Bills step up and finally reach the Super Bowl? Do the Rams have what it takes to defend their crown? The first game of the NFL season is sure to be one that excites. 

Week 4: Chiefs @ Buccaneers 

A Super Bowl 55 rematch sees Patrick Mahomes and the Chiefs visit Tom Brady and the Buccaneers. These two QBs will always be linked together in terms of greatness, as Mahomes is seen as Brady’s successor… if he ever retires. Expect a lot of scoring in this highly anticipated rematch. 

Week 1: Broncos @ Seahawks

Wow, Week one is exciting. Russell Wilson’s return to Seattle happens immediately after the trade, and both teams will have something to prove. Wilson and the Broncos are a major story in the NFL this year, and their first impression will most certainly be big one. 

Week 15: Rams @ Packers

Two of the best teams in the NFC face off in a matchup that could have playoff implications in terms of home field advantage. Green Bay won last years matchup but don’t be surprised if LA take the win this year. 

Week 2: Chargers @ Chiefs

Two of the best offenses in the league led by two of the best young quarterbacks in the league. What’s not to love? This early division matchup sparks the rivalry right away, which means the stakes for the second matchup will be even higher. 

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