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NFL Schedule Release: Ranking the Top 5 Games in 2022

By Nick Fata
Quarterback Josh Allen will lead the Bills against the Rams on Sept. 8.
© Jamie Germano / USA TODAY NETWORK
  • 09/08 8:20 PM ET
    Spread
    ML
    Total
    451BUFBUF
    +1-110
    -105
    52-110 o
    452LARLAR
    -1-110
    -115
    52-110 u
    Betting Angle
    BUFFALO is 19-7 ATS (11.3 Units) in games played on turf in the last 3 seasons.
  • 09/11 8:20 PM ET
    Spread
    ML
    Total
    479TBTB
    -2-110
    -130
    52-110 o
    480DALDAL
    +2-110
    +110
    52-110 u
    Betting Angle
    DALLAS are 7-0 ATS (7 Units) in the 1rst half of the season in the last 2 seasons.
  • 09/11 1:00 PM ET
    Spread
    ML
    Total
    453BALBAL
    -5-110
    -200
    45-110 o
    454NYJNYJ
    +5-110
    +170
    45-110 u
    Betting Angle
    BALTIMORE is 0-7 ATS (-7.7 Units) as a favorite of 3.5-10.5 pts. in the last 2 seasons.
  • 09/11 1:00 PM ET
    Spread
    ML
    Total
    455NONO
    -3.5-110
    -160
    42-110 o
    456ATLATL
    +3.5-110
    +140
    42-110 u
    Betting Angle
    ATLANTA is 0-7 ATS (-7.7 Units) in home games in the last 2 seasons.
  • 09/11 4:25 PM ET
    Spread
    ML
    Total
    471KCKC
    -3-110
    -150
    53-110 o
    472ARZARZ
    +3-110
    +130
    53-110 u
    Betting Angle
    ARIZONA is 1-8 ATS (-7.8 Units) at home when the total >=49.5 in the last 3 seasons.
  • 09/11 1:00 PM ET
    Spread
    ML
    Total
    459CLECLE
    -4.5-110
    -180
    43.5-110 o
    460CARCAR
    +4.5-110
    +160
    43.5-110 u
    Betting Angle
    CLEVELAND is 16-4 Under (11.6 Units) against the NFC South since 1992.
  • 09/12 8:15 PM ET
    Spread
    ML
    Total
    481DENDEN
    -4-110
    -170
    41-110 o
    482SEASEA
    +4-110
    +150
    41-110 u
    Betting Angle
    DENVER is 36-19 ATS (15.1 Units) in the 1rst 2 weeks of the season since 1992.

The 2022 NFL schedule has finally been released, and to say there are a few matchups to look out for would be an understatement. But, if we have to pick, here are a few key exciting matchups to look out for this season.

Week 1: Bills @ Rams

The Buffalo Bills are arguably the best team in football… maybe behind the defending Super Bowl Champion Los Angeles Rams. Not only will this game be fun to watch, but also an early prove it game for both teams. Can the Bills step up and finally reach the Super Bowl? Do the Rams have what it takes to defend their crown? The first game of the NFL season is sure to be one that excites. 

Week 4: Chiefs @ Buccaneers 

A Super Bowl 55 rematch sees Patrick Mahomes and the Chiefs visit Tom Brady and the Buccaneers. These two QBs will always be linked together in terms of greatness, as Mahomes is seen as Brady’s successor… if he ever retires. Expect a lot of scoring in this highly anticipated rematch. 

Week 1: Broncos @ Seahawks

Wow, Week one is exciting. Russell Wilson’s return to Seattle happens immediately after the trade, and both teams will have something to prove. Wilson and the Broncos are a major story in the NFL this year, and their first impression will most certainly be big one. 

Week 15: Rams @ Packers

Two of the best teams in the NFC face off in a matchup that could have playoff implications in terms of home field advantage. Green Bay won last years matchup but don’t be surprised if LA take the win this year. 

Week 2: Chargers @ Chiefs

Two of the best offenses in the league led by two of the best young quarterbacks in the league. What’s not to love? This early division matchup sparks the rivalry right away, which means the stakes for the second matchup will be even higher. 

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